Definition of perforin in English:


Line breaks: per|forin
Pronunciation: /ˈpəːfərɪn


[mass noun] Biochemistry
  • A protein, released by killer cells of the immune system, which destroys targeted cells by creating lesions like pores in their membranes.
    More example sentences
    • The CD8 cells of long-term nonprogressors produce more perforin than do CD8 cells of HIV-positive people who developed AIDS, the scientists found.


1980s: from the verb perforate + -in1.

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