Definition of pico- in English:

pico-

Pronunciation: /ˈpiːkəʊ, ˈpʌɪkəʊ/

combining form

1(Used in units of measurement) denoting a factor of 10−12: picosecond
1.1Very small: picornavirus

Origin

from Spanish pico, literally 'beak, peak, little bit'.

Definition of pico- in:

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Word of the day internecine
Pronunciation: ˌintərˈnesēn
adjective
destructive to both sides in a conflict