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pleomorphism Line breaks: pleo|morph|ism
Pronunciation: /ˌpliːə(ʊ)ˈmɔːfɪz(ə)m/

Definition of pleomorphism in English:


[mass noun]
The occurrence of more than one distinct form of a natural object, such as a crystalline substance, a virus, the cells in a tumour, or an organism at different stages of the life cycle.
Example sentences
  • Vascular invasion, mitosis, and cell pleomorphism are not observed in cases of bronchiolitis obliterans organizing pneumonia.
  • Mitosis, size of tumour, necrosis and pleomorphism are thought to be prognostic factors for aggressiveness of solitary fibrous tumours.
  • Several histologic findings, including increased number and size of cells, greater nuclear pleomorphism, and increased mitotic activity, suggest a well-differentiated fibrosarcoma.


Example sentences
  • They separated the tumors into 4 types: ceruminous gland adenocarcinoma, ceruminous adenoma, adenoid cystic carcinoma, and pleomorphic adenoma.
  • The tumor cells had slightly eosinophilic cytoplasm and pleomorphic nuclei with prominent nucleoli.
  • The sarcomatous component featured pleomorphic, plump spindle cells with prominent mitoses.


Mid 19th century: from Greek pleiōn 'more' + morphē 'form' + -ism.

Definition of pleomorphism in:
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