Definition of prodrug in English:

prodrug

Line breaks: pro|drug
Pronunciation: /ˈprəʊdrʌg
 
/

noun

A biologically inactive compound which can be metabolized in the body to produce a drug.
More example sentences
  • This involves gene transfer of an enzyme into tumour cells, which converts an inactive prodrug into a toxic metabolite, leading to cell death.
  • The influence of branching on the enzymatic stability of the compounds was investigated, as it is known that sterically hindered ester prodrugs are more stable toward enzymatic hydrolysis.
  • Bouncing powerful X-rays off the protein crystals yielded a three-dimensional image of the dual protein structure, showing them exactly how the prodrug and the enzyme interact.

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