Definition of senescence in English:

senescence

Line breaks: sen|es¦cence
Pronunciation: /sɪˈnɛs(ə)ns
 
/

noun

[mass noun] Biology
  • 1The condition or process of deterioration with age.
    More example sentences
    • Although it is characterized as being a deterioration process, senescence is considered to be a highly evolved genetic process.
    • But most healthy mammalian cells managed just a few dozen divisions before they stopped, a process known as replicative senescence.
    • Oxidative processes during senescence involve an increase in enzyme activities generating oxygen radicals and superoxide ions.
  • 1.1Loss of a cell’s power of division and growth.
    More example sentences
    • We have devised a functional approach to clone genes involved in the regulation of cell growth and senescence.
    • Mortality barriers to human cell immortalization and effectors of replicative cellular senescence in human cells
    • The terms senescence and programmed cell death have led to some confusion.

Derivatives

senescent

adjective
More example sentences
  • It is known that induction of telomere shortening leads to the extinction of yeast clones similar to a senescent phenotype.
  • A feature shared by senescent cells in culture and in vivo is shortening of the telomeres.
  • The molecular mechanisms for vacuolar protein degradation and the nutrient recycling pathway in senescent leaves are generally not clear.

More definitions of senescence

Definition of senescence in:

Get more from Oxford Dictionaries

Subscribe to remove ads and access premium resources

Word of the day coloratura
Pronunciation: ˌkələrəˈto͝orə
noun
elaborate ornamentation of a vocal melody