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senescence

Line breaks: sen|es¦cence
Pronunciation: /sɪˈnɛs(ə)ns
 
/

Definition of senescence in English:

noun

[mass noun] Biology
1The condition or process of deterioration with age.
Example sentences
  • Although it is characterized as being a deterioration process, senescence is considered to be a highly evolved genetic process.
  • But most healthy mammalian cells managed just a few dozen divisions before they stopped, a process known as replicative senescence.
  • Oxidative processes during senescence involve an increase in enzyme activities generating oxygen radicals and superoxide ions.
1.1Loss of a cell’s power of division and growth.
Example sentences
  • We have devised a functional approach to clone genes involved in the regulation of cell growth and senescence.
  • Mortality barriers to human cell immortalization and effectors of replicative cellular senescence in human cells
  • The terms senescence and programmed cell death have led to some confusion.

Derivatives

senescent

1
adjective
Example sentences
  • It is known that induction of telomere shortening leads to the extinction of yeast clones similar to a senescent phenotype.
  • A feature shared by senescent cells in culture and in vivo is shortening of the telomeres.
  • The molecular mechanisms for vacuolar protein degradation and the nutrient recycling pathway in senescent leaves are generally not clear.

Definition of senescence in:

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