Definition of sickle-cell anaemia in English:

sickle-cell anaemia

Line breaks: sickle-cell an|aemia
(also sickle-cell disease)

noun

[mass noun]
  • A severe hereditary form of anaemia in which a mutated form of haemoglobin distorts the red blood cells into a crescent shape at low oxygen levels. It is commonest among those of African descent.
    More example sentences
    • Infection can produce severe anaemia and an aplastic crisis in people with sickle-cell anaemia or other abnormalities of haemoglobin.
    • In sickle-cell disease, the haemoglobin is abnormal and this causes a change in the shape of the red blood cells.
    • The blood condition sickle-cell anaemia is most common in people from Africa, the Caribbean, the eastern Mediterranean, the Middle East and Asia.

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Pronunciation: ˌkələrəˈto͝orə
noun
elaborate ornamentation of a vocal melody