A subordinate or secondary form.
- These studies, by and large, do not enroll patients with the subforms of depression that respond more favorably to antidepressants and are plagued by ‘inflation’ of entry symptom severity thresholds.
- Serum markers such as aspartate transaminase, lactate dehydrogenase, and lactate dehydrogenase subforms no longer are used because they lack cardiac specificity and their delayed elevation precludes early diagnosis.
- Early markers of acute ischemia include myoglobin and creatine kinase-MB subforms, when available.
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