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substituent Line breaks: sub¦stitu|ent
Pronunciation: /səbˈstɪtjʊənt/

Definition of substituent in English:


An atom or group of atoms taking the place of another atom or group or occupying a specified position in a molecule: displacement of alkyl substituents [as modifier]: the presence of substituent hydrogen atoms
More example sentences
  • In an interstitial solid solution, substituent atoms or ions are added to void spaces (interstitial sites) between normal atomic sites.
  • Under rigorous conditions benzene will undergo substitution for one of its hydrogen substituents, by a process called electrophilic aromatic substitution.
  • Any groups attached to the main chain are called substituents, they are there in place of hydrogen atoms.


Late 19th century: from Latin substituent- 'standing in place of', from the verb substituere (see substitute).

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