Definition of tacrine in English:

tacrine

Line breaks: tac|rine
Pronunciation: /ˈtakriːn
 
/

noun

[mass noun] Medicine
  • A synthetic drug used in Alzheimer’s disease to inhibit the breakdown of acetylcholine by cholinesterase and thereby enhance neurological function.
    • An acridine derivative; chemical formula: C13H15N2Cl
    More example sentences
    • The cholinesterase inhibitor tacrine is used rarely because of potential liver toxicity and the need for frequent laboratory monitoring.
    • These effects are comparable to those of the drug tacrine, which is prescribed for Alzheimer's disease.
    • The pharmacologic characteristics and side effects of tacrine make it a second-line agent.

Origin

1960s: from t(etra-) + acr(id)ine.

More definitions of tacrine

Definition of tacrine in:

Get more from Oxford Dictionaries

Subscribe to remove ads and access premium resources

Word of the day maelstrom
Pronunciation: ˈmālˌsträm
noun
a powerful whirlpool in the sea