1 Physiology A cell which bears receptors for a hormone, drug, or other signalling molecule, or is the focus of contact by a virus, phagocyte, nerve fibre, etc.
- When the hormone reaches its target cell, it locks onto the cell's specific receptors and these hormone-receptor combinations transmit chemical instructions to the inner workings of the cell.
- Interaction with the receptor of the target cell may be essential for this conformational change and the conformation itself.
- In this model, electrostatic interactions between the virus, target cell, and charged polymers determine the nature and magnitude of the driving force for virus adsorption.
2 Medicine An abnormal form of red blood cell which appears as a dark ring surrounding a dark central spot, typical of certain kinds of anaemia.
- The more common episomal pattern appears as a dense, opaque, blue oval that overlies the majority of the central portion of the target cell.
- The second model is based on a stem cell hierarchical framework in which the target cell is a cancer stem cell that may give rise to cells capable of reinitiating the tumor and cells that have limited capacity to differentiate.
- The lack of pulsation in the middle of a target cell as opposed to a healthy specimen is due to the fact that the cell membrane has collapsed on itself.
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