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senile US English

(Of a person) having or showing the weaknesses or diseases of old age, especially a loss of mental faculties

senile US Thesaurus

she's in her nineties, but she's not a bit senile

senile plaque US English

A microscopic mass of fragmented and decaying nerve terminals around an amyloid core, numbers of which occur in the brains of people with Alzheimer’s disease

senile dementia US English

Severe mental deterioration in old age, characterized by loss of memory and control of bodily functions

presenile US English

Occurring in or characteristic of the period of life preceding old age