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Words spelled with -oe/-ae

British English words that are spelled with the double vowels ae or oe are usually spelled with just an e in American English:

US British
leukemia leukaemia
maneuver manoeuvre
estrogen oestrogen
pediatric paediatric

Note that in American English, certain terms, such as archaeology, retain the ae spelling as standard, although the spelling with just the e (e.g., archeology) is usually acceptable as well.

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Grammar and usage